Tuba Büyüküstün was born on July 5, 1982 in Istanbul. She is of Crimean immigrant origin on her mother's side and Cretan immigrant on her father's side. She graduated from Istanbul Private Doğuş Schools and Mimar Sinan Fine Arts University, Department of Stage Decorations and Costume Design.
She has appeared in commercials while studying at University. After graduating from university, he started acting thanks to director Tomris Giritlioğlu.
In 2004, she made a name for herself by portraying the character of Zarife in the TV series Çembermde Gül Oya, directed by Çağan Irmak and broadcast on Kanal D. In the same year, Büyüküstün played the character of Gülizar in the television movie Gülizar directed by Cemal Şan.
She received the Best Actress Award at the Serbia-Montenegro International TV Festival Bar for her role. In 2005, he made a big break by sharing the lead role with Bülent İnal and Sinan Tuzcu in the TV series Ihlamurlar Altında, directed by Aydın Bulut and broadcast on Kanal D.

In the same year, he played the character of Aysun in the movie "My Father and My Son" and once again worked with Çağan Irmak and stepped into the cinema. Büyüküstün, who played in the movie named Exam, directed by Ömer Faruk Sorak in 2006, is the famous actor in this movie.
He had the opportunity to work with Jean-Claude Van Damme. In 2007, she shared the lead role with Murat Yıldırım and Çetin Tekindor in the TV series Asi, directed by Cevdet Mercan and broadcast on Kanal D, shot in Antakya. In the same years, Gül Oya in my Circle,
With his TV series Ihlamurlar Altında and Asi being shown on Arab television, he gained a great reputation in the Middle East and played an important role in the export of Turkish TV series abroad. Asi TV series starring
With its ratings in 67 countries, it was nominated for the Best Soap Series category at the 51st Monte-Carlo Television Festival. later on atv
She shared the lead role with Cansel Elçin in the TV series Gönülçelen. In the first days of 2013, he shared the lead role with İlker Aksum in the TV series 20 Minutes, which started to be broadcast on Star TV, and took a 1.5-year break.
is back. She was nominated for the Best Actress category at the 42nd International Emmy Awards for her role in the TV series 20 Minutes and became the first Turkish actress to be nominated for an Emmy.[5] In 2014, he was selected as the goodwill ambassador of UNICEF Turkey.
Büyüküstün shared the lead role with Engin Akyürek in the TV series Kara Para Aşk, which started in March 2014 and was broadcast on ATV. While receiving the Stars of Export award for his role in the TV series Kara Para Aşk, he also played this role and
She was named Best Actress at the 14th International Giuseppe Sciacca Awards for her charity. In the last months of 2015, he focused on cinema, one of which was a short film, Orman, Memories of the Wind and
He acted in Tight Dress movies. In 2016, Büyüküstün played in the famous director Ferzan Özpetek's movie "Istanbul Kırmızısı" with important actors such as Halit Ergenç, Mehmet Günsür and Nejat İşler.

He shared the lead role with Kıvanç Tatlıtuğ in the series Brave and Beautiful, which started in November and was broadcast on Star TV. In 2020, Rise of Empires, published on the internet platform Netflix:
She played Mara Hatun in the Ottoman TV series. Again in 2020, he became a guest actor by reviving himself in the series Ara My Manager, which was broadcast on Star TV, and returned to the TV screens after 4 years.
After Neslihan Atagül left the series due to health problems in the Sefirin Kızı series, starring Engin Akyürek and Neslihan Atagül, which was broadcast on Star TV in 2021, she was included in the series as the leading role.
He revived the character of Blue. Finally, he continues his cinema life with the movie published on netfilix and starring Murat Boz, Seda Minister, Boncuk Yılmaz.
On July 28, 2011, she married Onur Saylak, an actress like herself. She gave birth to her twin daughters on January 19, 2012. He named his daughters Toprak and Maya. Their marriage ended on June 5, 2017